ArQule Inc (NASDAQ:ARQL) has presented their data at the AACR-NCI-EORTC meeting in Boston which clearly demonstrates the capabilities of Company’s proprietary drug discovery platform to generate a class of small molecules that has significant therapeutic potential. The data reflected the results of the application of the ArQule Kinase Inhibitor Platform (AKIP) to discover and optimize a series of small molecule inhibitors of fibroblast growth factor receptor (FGFR) that are not ATP-competitive and that show potent anti-tumor activity in FGFR-driven cancer models.

ArQule is a biotechnology company which looks after the research and development of next-generation, small-molecule cancer therapeutics. The Company’s targeted, broad-spectrum products and research programs are focused on key biological processes that are central to cancer. ArQule’s current discovery efforts, which are based on the ArQule Kinase Inhibitor Platform (AKIP™)

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Micromet’s (MITI) third-quarter loss per share came in at 22 cents, well below the Zacks Consensus Estimate of 14 cents and a loss of 15 cents in the prior-year period. The company reported revenues of $4 million, compared to $7 million in the third quarter of 2008. Micromet records revenues primarily in the form of reimbursements of expenses incurred by the company under different collaborative agreements. We believe current investor focus is more on the developments of the company’s portfolio rather than the financials.

Operating expenses during the quarter increased 28% year over year to $17.13 million, primarily due to a 34% rise in R&D expenses. The increase in R&D expenses was driven by Micromet assuming full responsibility of the development of its lead candidate blinatumomab as per the company’s agreement with MedImmune.

As a reminder, earlier this month, Micromet had agreed to buy out MedImmune's option to reacquire the right

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MannKind Pharma’s (MNKD) third quarter loss per share came in at 42 cents, better than the Zacks Consensus Estimate of 49 cents and loss of 67 cents reported in the year-ago period. The company does not have any revenue stream at present -- its lead product, Afresa (inhaled insulin for the treatment of type I and type II diabetes) is currently under US Food and Drug Administration (FDA) review. MannKind filed a New Drug Application (NDA) for Afresa with the FDA in March 2009, which was subsequently accepted in May 2009. The company has been assigned a Prescription Drug User Fee Act (PDUFA) date of January 16, 2010. Operating expenses for the third quarter declined 38% to $42.8 million, primarily due to a huge reduction in R&D expenses. Reduced costs associated with the clinical development of Afresa along with a decline in manufacturing costs brought down ...

BSD Medical Corporation (NASDAQ:BSDM) today announced that their published study results demonstrated improvement in the overall survival, tumor response rates, and local tumor control from the addition of hyperthermia therapy delivered through BSD-2000 Hyperthermia System. This therapy was delivered as a standard treatment regimen for the 45 patients suffering from high-risk bladder cancer.

The multi-institutional study was named as Quadrimodal treatment of high risk T1 and T2 bladder cancer. The research was conducted by eight well-known medical researchers who are the front-runners in the field of oncology research. The study was conducted at three prestigious medical centers one being one of the largest universities in Germany, University of Erlangen, which provides an unique range of interdisciplinary research, and also at University of Frankfurt and Hospital Martha-Maria in Germany. The study was published in Radiotherapy and Oncology which is the official publication of the European Society for Therapeutic Radiology and

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Champions Biotechnology, Inc., a leader in the development of advanced preclinical platforms and tumor-specific data to enhance and accelerate the value of oncology drugs, recently announced that the company has secured an agreement with Ortho Biotech Oncology Research & Development for the evaluation of a novel preclinical oncology therapeutic in Champions’ Biomerk Tumorgraft™ platform.

Preliminary studies show that Tumorgrafts closely reflect human cancer biology and their response to drugs is predictive of clinical outcomes in cancer patients. The company utilizes its preclinical platform to evaluate potential drugs and to create a portfolio of novel therapeutic candidates. After completing early-stage development, Champions Biotechnology intends to sell, partner or license the company’s portfolios to pharmaceutical and/or biotechnology companies.

Doug Burkett, Ph.D., president of Champions Biotechnology, Inc., stated, “We are excited to expand this ongoing collaboration in the development of innovative therapeutics in oncology. We continue to grow our customer base and revenues

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Yesterday, GlaxoSmithKline (GSK) received some good news with the US Food and Drug Administration’s (FDA) approval of Votrient (pazopanib) for the treatment of patients with advanced renal cell carcinoma (RCC), a form of kidney cancer. However, the FDA approval does not come as a surprise to us as earlier this month the FDA’s Oncologic Drugs Advisory Committee (ODAC) had voted unanimously in favor of the drug.  The favorable recommendation was based on encouraging results from a phase III trial of Votrient, in which the drug reduced the risk of tumor progression or death by 54% compared to placebo, regardless of prior treatment. The overall median progression-free survival (PFS) was 9.2 months with Votrient and 4.2 months with placebo.  For both treatment naïve patients and those who received cytokine-based treatment, the median PFS was better with Votrient – 11.1 months versus 2.8 months with placebo, and 7.4 ...

Cancer is a deadly killer that has been affecting families globally for far too long. Despite billions of dollars placed into research, there has not been a great amount of success in helping victim’s survive the tragic battle. One company in Maryland has developed a vaccine to stimulate a patient’s own immune system to fight cancer. That company is Northwest Biotherapeutics; their vaccine is the DCVaxA-Brain.

The DCVaxA-Brain is a groundbreaking vaccine because it is made up of the patient’s own “dendritic cells”, master cells that direct the immune system. The “dendritic cells” have been activated and educated to mobilize the whole immune system to recognize and destroy cancer cells bearing the biomarkers of the patients own tumor.

Today, Northwest Biotherapeutics announced further long-term data for the period from January through September of 2009 from its prior Phase I and Phase I/II clinical trials conducted at UCLA with

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BEVERLY, Mass., Oct. 19, 2009 (GLOBE NEWSWIRE) — Cellceutix Corporation (OTCBB:CTIX) today announced that data recently presented by the Company at the American Association for Cancer Research (AACR) along with other data developed by the Company indicate that Kevetrin is selectively targeting very specific anti-tumor pathways, such as AKT and p38 MAP kinase. The data presented at the AACR showed that Kevetrin was less cytotoxic than paclitaxel, cisplatin and 5FU while having better anti-tumor activity in two multi-drug resistant lung cancer cell lines. This indicates that Kevetrin is not acting primarily as a cytotoxic agent but may be targeting specific components of the signal transduction pathway, such as AKT and p38 MAP kinase. The Company is continuing to explore other potential targets.

Other data developed by the Company indicate that Kevetrin has potent anti-tumor activity in one cell line (MDA-MB–231) despite only partially inhibiting AKT in that cell line.

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HDVY, Health Discovery Corporation, HDVY.OB

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The United States Patent and Trademark Office (USPTO) issued a patent to HDVY that includes additional, broader claims to the HDVY’s exclusive Recursive Feature Elimination (RFE) using Support Vector Machines (“SVM”) or SVM-RFE method, the first patent for which issued in 2006. The SVM-RFE method has been used to successfully identify the most important pieces of information needed to solve complex pattern-recognition problems and has been shown in numerous peer-reviewed publications from some of the worlds top academic institutions to be a superior technology

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Kevetrin(TM) Shows Excellent Activity in Animal Models of Drug Resistant Lung Cancer With Less Cytotoxicity Than Paclitaxel

Cellceutix of Beverly, MA, to Pursue Development for Drug-Resistant Lung Cancer

BEVERLY, Mass., Oct. 13, 2009 (GLOBE NEWSWIRE) — Cellceutix Corporation (OTCBB:CTIX) today announced that it presented a poster and its Chief Scientific Officer, Dr. Krishna Menon, was one of only four individuals selected to participate in an expert panel discussion of the abstract at the American Association for Cancer Research (AACR) meeting “Frontiers in Basic Cancer Research” in Boston, MA on October 10, 2009. The Company’s poster describes in vitro and in vivo research on its lead compound, Kevetrin(TM), which is being developed for drug resistant cancers. The three day AACR meeting featured presentations on the latest advances in basic cancer research from around the world. The AACR issued a press release on October 10, 2009 which featured the abstract submitted

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